IRB+ alternative

A modern IRB+ alternative for teams outgrowing legacy IRB databases.

If your IRB office is evaluating IRB+, replacing it, or trying to add online submission without another operational layer, ConductCompliance gives you a cleaner path: modern intake, reviewer queues, letters, audit trails, reporting, and migration support.

Target the IRB+ buyer moment

Replacing legacy workflow

Move from database-plus-email operations to a modern review portal.

Online submission upgrade

Offer PI intake, admin triage, reviewer routing, and packet generation.

Migration path

Bring over studies, people, documents, forms, letters, and audit context.

Why teams search for an alternative

The job is bigger than tracking submissions.

Modern submission intake

PIs and coordinators need a guided portal, not instructions scattered across email.

Operational visibility

Administrators need fast status, review, letter, and audit context without exporting everything first.

Migration confidence

The replacement system has to respect historical data and local review rules.

Source grounding

This comparison uses public IRB+ pages reviewed on May 26, 2026. Product fit and pricing should be confirmed directly with each vendor before purchase.

IRB database core

Studies, documents, users, determinations, review state, and audit history stay organized in one workspace.

Submission packet operations

PI intake, supporting rationale, documents, reviewer comments, and determination materials stay tied together.

Reporting and exports

Keep ad hoc reporting and export workflows while reducing spreadsheet-only operational drift.

Compliance guardrails

Decision support stays explicit: the local IRB remains the authority, with audit trails and source context preserved.

Practical comparison

Match the familiar IRB database needs, then modernize the workflow around them.

IRB+ public materials emphasize online submission, letters, agendas, minutes, search, Excel export, customizable fields, and tracked compliance data. Those are real requirements. ConductCompliance treats them as the base layer and builds toward a more integrated review operating system.

WorkflowIRB+ public materialsConductCompliance approach
Online submissionPublic IRB+ materials describe online submission for protocols, continuing reviews, amendments, adverse events, and related items.ConductCompliance adds a modern PI portal with structured intake, reviewer routing, and versioned documents.
Letters and templatesIRB+ lists more than 120 built-in customizable letters and one-click email letters.ConductCompliance supports determination-letter workflows with citation-grounded packet context and audit history.
Agenda and minutesIRB+ lists agenda and minute generation.ConductCompliance supports board workflow primitives and routes studies through reviewer and admin queues.
Reporting and exportsIRB+ lists grid search, ad hoc reports, and Excel export.ConductCompliance keeps exportability, audit events, and operational dashboards in the same workspace.
Tracked entitiesIRB+ lists conflicts, HUDs, drugs, devices, SAEs, fees, audits, training dates, and more.ConductCompliance targets the same compliance workload while adding AI-assisted packet generation and modern account/admin controls.
IACUC expansionIRB+ public materials are IRB-focused.ConductCompliance now includes IACUC protocol drafting and a ConductScience anesthesia/ventilation handoff path.

Shortlist ConductCompliance before you renew legacy IRB software.

Use the demo to test intake, review, admin, reporting, and migration assumptions against your current IRB workflow.

Migration plan
Need migration detail first? Review the IRB+ migration plan.