IRB software comparison
ConductCompliance vs IRB+: modern IRB operations without the legacy handoff.
IRB+ has public materials for an affordable IRB database with online submission. ConductCompliance targets the same operational buyer, then adds modern intake, reviewer workflows, AI-assisted packet work, IACUC support, and a cleaner migration path.
Target the IRB+ buyer moment
Replacing legacy workflow
Move from database-plus-email operations to a modern review portal.
Online submission upgrade
Offer PI intake, admin triage, reviewer routing, and packet generation.
Migration path
Bring over studies, people, documents, forms, letters, and audit context.
Feature comparison
Where the workflows overlap, and where ConductCompliance moves faster.
The practical question is not whether a system can store IRB records. It is whether your staff can run submission intake, committee routing, reviewer work, letters, reports, and migrations without stitching the day together in email and spreadsheets.
Source grounding
This comparison uses public IRB+ pages reviewed on May 26, 2026. Product fit and pricing should be confirmed directly with each vendor before purchase.
| Workflow | IRB+ public materials | ConductCompliance approach |
|---|---|---|
| Online submission | Public IRB+ materials describe online submission for protocols, continuing reviews, amendments, adverse events, and related items. | ConductCompliance adds a modern PI portal with structured intake, reviewer routing, and versioned documents. |
| Letters and templates | IRB+ lists more than 120 built-in customizable letters and one-click email letters. | ConductCompliance supports determination-letter workflows with citation-grounded packet context and audit history. |
| Agenda and minutes | IRB+ lists agenda and minute generation. | ConductCompliance supports board workflow primitives and routes studies through reviewer and admin queues. |
| Reporting and exports | IRB+ lists grid search, ad hoc reports, and Excel export. | ConductCompliance keeps exportability, audit events, and operational dashboards in the same workspace. |
| Tracked entities | IRB+ lists conflicts, HUDs, drugs, devices, SAEs, fees, audits, training dates, and more. | ConductCompliance targets the same compliance workload while adding AI-assisted packet generation and modern account/admin controls. |
| IACUC expansion | IRB+ public materials are IRB-focused. | ConductCompliance now includes IACUC protocol drafting and a ConductScience anesthesia/ventilation handoff path. |
Positioning
For teams that want an IRB+ alternative, not just another database.
IRB+ public pricing separates the base administrator product, per-user hosting, read-only users, and a newer online submission module. ConductCompliance packages the buyer conversation around a complete review workspace: intake, study workspace, reviewer queue, admin controls, document versioning, audit events, and modern account flows.
The migration pitch is simple: keep the historical record, move the active workflow, and stop making coordinators reconcile protocol status across exports, inboxes, and shared folders.
Read the IRB+ alternative pageIRB database core
Studies, documents, users, determinations, review state, and audit history stay organized in one workspace.
Submission packet operations
PI intake, supporting rationale, documents, reviewer comments, and determination materials stay tied together.
Reporting and exports
Keep ad hoc reporting and export workflows while reducing spreadsheet-only operational drift.
Compliance guardrails
Decision support stays explicit: the local IRB remains the authority, with audit trails and source context preserved.
Evaluate ConductCompliance as your IRB+ alternative.
Bring your current workflow, exports, and local review rules. We will show what migrates cleanly, what needs mapping, and what should stay archived.